Activity of a nitrofurazone matrix urinary catheter against catheter-associated uropathogens

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Activity of a nitrofurazone matrix urinary catheter against catheter-associated uropathogens.

Nitrofurazone-coated urinary catheter segments inhibited 51 (75%) of 70 urinary bacterial isolates from patients with indwelling catheters. Inhibition zones correlated significantly with the nitrofurazone MIC (r2 = 0.79, P = 0.0001). All strains except the Pseudomonas spp. were inhibited by < or = 64 micrograms of nitrofurazone per ml. MICs of nitrofurazone and nitrofurantoin correlated signifi...

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Antibacterial Modification of Intravascular Catheter Surface for the Prevention of Catheter-Associated Infection

Objective: Intravascular catheter-associated infection has been increasing hospitalization in post-surgery patients mainly due to microbial colonization of the catheter surface and formation of a superficial biofilm layer. The present study is aimed in developing an effective antibacterial device which can prevent colonization of organisms by modification of catheter. Methods: In the present st...

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Catheter-associated urinary tract infection.

OBJECTIVES To study the incidence, risk factors, clinical outcomes and antibiotic costs of catheter-associated urinary tract infections (CAUTI) in patients with indwelling urinary catheter for one week and longer MATERIAL AND METHOD Patients in neurology and neurosurgery wards in a teaching hospital were studied. Patients with UTI before catheterization and in whom the catheter was removed be...

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Microbial Profile and Antimicrobial Susceptibility Pattern of Uropathogens Isolated From Catheter Associated Urinary Tract Infection (CAUTI)

Urinary Tract Infections (UTIs) are defined as diseases which are caused by a microbial invasion of the genitourinary tract that extends from the renal cortex of the kidney to the urethral meatus 2 . Among UTIs acquired in the hospital, approximately 75% are associated with a urinary catheter 3 . Catheter associated urinary tract infection (CAUTI) is one of the most important Device associated ...

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Prevention of catheter-associated urinary tract infection.

PURPOSE OF REVIEW The underlying cause of catheter-associated urinary tract infection is biofilm formation by uropathogens on the urinary catheter. Biofilm is a relatively new concept in medicine, and current measures to prevent biofilm formation are inadequate. Considerable work is being done in this area, but little clinical progress has been made. The purpose of this review is to analyze rec...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1993

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.37.9.2033